NFL Preseason Betting: Cardinals vs Broncos Odds, Picks 8/25. If you’re looking for a Sunday pick-me-up, I’ve got just the ticket for you — betting on the Denver Broncos to cover the -3.5 NFL spread against the Arizona Cardinals. And let’s be honest, betting on the Cardinals this preseason is like betting on a one-legged man in a sack race. Sure, they might make it to the end, but it won’t be pretty. NFL Preseason Betting: Cardinals vs Broncos Odds, Picks August 25, 2024 Bo Nix #10 of the Denver Broncos - Jamie Schwaberow/Getty Images/AFP Cardinals vs Broncos Game Information Game: Cardinals vs Broncos Location: Empower Field, Denver, CO Day/Time: Sunday, Aug. 25, 4:30 p.m. ET Cardinals vs Broncos Live Stream: NFL Game Pass On the other hand, the Broncos have been a well-oiled machine, cruising through their preseason matchups like they’ve got something to prove. And with the Cardinals coming to town for a rematch of last year’s preseason nail-biter, this looks like the perfect opportunity to back Denver and ride that Mile High wave to victory. Cardinals vs Broncos Odds and Spreads Cardinals vs Broncos Betting Keys Let’s start by addressing the elephant — or the Cardinal — in the room. Arizona has had a rough preseason, to say the least. The Cardinals dropped their first two games, stumbling against the Saints and then tripping over their feet against the Colts. Sure, Clayton Tune has shown some promise with his passing game, but it’s hard to take him seriously when his offensive line is about as sturdy as a wet paper bag.